PLA2R-IgG4 antibody as a predictive biomarker of treatment effectiveness and prognostic evaluation in patients with idiopathic membranous nephropathy: a retrospective study.

PeerJ(2022)

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摘要
We found that the patients in the RTX group and CTX group achieved effective remission of proteinuria after 12 months of treatment. PLA2R-IgG4 may be a more effective biomarker for treatment effectiveness analysis and prognostic assessment, compared with anti-PLA2R-IgG for PLA2R associated IMN.
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关键词
Idiopathic membranous nephropathy,IgG4,M-type phospholipase A2 receptor,Rituximab,Time-resolved fluoroimmunoassay
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