Heterogeneous persistence of Mycobacterium leprae in oral and nasal mucosa of multibacillary patients during multidrug therapy.

Arthur da Silva Neumann,Amanda Nogueira Brum Fontes,Márcia Quinhones Pires Lopes,Philip Noel Suffys,Milton Ozório Moraes,Flávio Alves Lara

Memorias do Instituto Oswaldo Cruz（2022）

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摘要

We concluded that qPCR of 16S rRNA for the determination of M. leprae viability in nasal and oral scraping samples could represent an interesting approach to monitor treatment efficacy.

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关键词

leprosy,nasal scrapings,oral scrapings,molecular viability,qPCR,treatment

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