An ultra-performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry method based on a four-step analysis strategy to investigate metabolites of Qi-Yu-San-Long decoction in rat plasma.

Yue Zhao,Yang Chen,Ruijuan Li,Ting Zheng,Mengwen Huang,Yating Gao,Zegeng Li,Huan Wu

Rapid communications in mass spectrometry : RCM（2023）

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摘要

In rat plasma, 101 xenobiotics of QYSLD were identified and their dynamic metabolic profiles were systematically delineated, which laid a material basis for further research of the pharmacodynamic substances of QYSLD inhibiting NSCLC.

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