Poster No. 045 the Role of 24-H Holter Monitoring in Thrombosis – a Single-Centre Subanalysis in the Young

Abstract Background Undercovering the etiology responsible for pathologic states is of the uttermost importance, especially regarding young people. Arterial and venous thromboembolism may have an impact on morbidity and mortality, enhancing the need to prevent recurrences. Material and methods Retrospective, single-centre analysis of 24-h Holter monitoring in patients with thrombotic events and less than 40 years during a 5-year period, using IBM® SPSS® software to perform descriptive analysis. Results and conclusions Thrombosis was the reason for requesting 24-h Holter monitoring in 7% (n = 41) from a total of 581 exams screened – 68.3% had a stroke, 6% a transient ischemic stroke, 4.9% a pulmonary embolism, 4.9% an intestinal ischemia and 2.4% had both pulmonary embolism and deep vein thrombosis. Patients had a median age of 35 ± 6 years, 63.7% were male and past medical history consisted of cardiovascular risk factors, particularly smoking (36.6%), high blood pressure (19.5%) and dyslipidemia (12.2%). Merely 4.9% had a diagnostic finding – atrial flutter and second-degree atrioventricular block Mobitz II. On the other hand, autoimmune tests were altered in 12.2% and echocardiogram revealed patent foramen ovale, atrial septum aneurysm and interatrial septum bulging with shunt in 9.8%, 2.4% and 2.4%, respectively. Regarding management, 78% were medicated with aspirin or anticoagulant and 4.9% were submitted to percutaneous closure of patent foramen ovale. Despite low prevalence of diagnostic findings, Holter monitoring is an important complementary exam that can have therapeutic implications in these cases and, consequently, in preventing new events.