Propranolol Reduces p-tau Accumulation and Improves Behavior Outcomes in a Polytrauma Murine Model

Kathleen E. Singer,Emily D. McGlone,Sean M. Collins,Taylor E. Wallen,Mackenzie C. Morris,Rebecca M. Schuster,Lisa G. England,Matthew J. Robson,Michael D. Goodman

Journal of Surgical Research（2023）

引用 2|浏览5

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摘要

Polytrauma including TBI generates high levels of hippocampal p-tau, but propranolol may help prevent this accumulation to improve both neuropathological and functional outcomes in males.

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关键词

Beta-blocker,Hemorrhage,Propranolol,p-tau,Traumatic brain injury

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