Chronic cerebral hypoperfusion-induced dysregulations of hyperpolarization-activated cyclic nucleotide-gated, KCNQ and G protein-coupled inwardly rectifying potassium channels correlated with susceptibility and unsusceptibility to anxiety behaviors.
Current neurovascular research（2022）
摘要
The different subunits of HCN, KCNQ and GirK channels in amygdale may contribute to distinct response to aversive stimuli or stress induced by CCH that evokes divergent influence on anxiety-like behavior in rats.
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关键词
GirK channel,HCN channel,KCNQ channel,affective disorders,chronic cerebral hypoperfusion,depression- and anxiety-like behavior
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