Molecular characteristics of pediatric nasopharyngeal carcinoma using whole-exome sequencing

Oral Oncology（2022）

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摘要

•We first reported the somatic and germline genetic aberrations in pNPC.•Patients with pNPC exhibited high level of PD-L1 expression.•Our results provide a deeper understanding of molecular genetics of pNPC.

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关键词

Pediatric nasopharyngeal carcinoma,Rare cancer,Pediatric cancer,Whole exome sequencing

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