The fullerene awakens

Recently in Angewandte Chemie, Kim and co-workers employed a large Zn-porphyrin paneled cage to activate C-60 toward inverse electron-demand Diels-Alder reaction with a tetrazine through pre-cise pre-organization of the reaction partners. Subsequent hydra-tion-induced rearrangement resulted in displacement of the reac-tion product, enabling catalytic turnover.