Senescent-like Blood Lymphocytes and Disease Progression in Amyotrophic Lateral Sclerosis.

Ozlem Yildiz,Johannes Schroth,Timothy Tree,Martin R Turner,Pamela J Shaw,Sian M Henson,Andrea Malaspina

Neurology(R) neuroimmunology & neuroinflammation（2023）

引用 4|浏览13

暂无评分

摘要

Our data suggest that a systemic elevation of senescent and late memory T and B lymphocytes is a feature of faster progressing ALS and of ALS individuals with bulbar involvement. Lymphocyte senescence and their memory state may be central to the immune dysregulation known to drive disease progression in ALS and a target for biomarkers and therapeutics discovery.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要