Tremor and Movement Slowness Are Two Unrelated Adverse Effects Induced by Valproate Intake.

Alessandro De Biase,Giulia Paparella,Luca Angelini,Antonio Cannavacciuolo,Donato Colella,Emanuele Cerulli Irelli,Anna Teresa Giallonardo,Carlo Di Bonaventura,Alfredo Berardelli,Matteo Bologna

Movement disorders clinical practice（2022）

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摘要

Tremor and movement slowness are motor signs induced by VPA. VIT severity is exacerbated when VPA is taken in combination with other antiepileptics. VPA-induced slowness occurs regardless of tremor, may precede tremor development, and is not attributed to epilepsy.

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关键词

bradykinesia,cerebellum,kinematic finger tapping,movement slowness,valproate‐induced tremor

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