In Multiple Myeloma, High-Risk Secondary Genetic Events Observed at Relapse Are Present From Diagnosis in Tiny, Undetectable Subclonal Populations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）
摘要
These data suggest that identifying these scarce aggressive cells may necessitate more aggressive treatment as early as diagnosis to prevent them from becoming the dominant clone.
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关键词
multiple myeloma,secondary genetic events,high-risk
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