The Preliminary Assessment of New Biomaterials Necessitates a Comparison of Direct and Indirect Cytotoxicity Methodological Approaches.

Polymers(2022)

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摘要
Comparison of both methods shows that it is pivotal to investigate biomaterials at the very early stages using both indirect and direct methods to access the influence of the released toxins and surface of the material on the cell condition.
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关键词
biomaterial evaluation,biomaterial toxicity testing,chitosan-bioglass biocomposite,direct and indirect toxicity tests
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