Structural and functional conservation of the activating Ca²⁺ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors

Cell calcium（2022）

引用 2|浏览6

暂无评分

摘要

Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) and Ryanodine Receptors (RyRs) dictate the release of Ca2+ from the Endoplasmic (ER) and Sarcoplasmic Reticulum (SR). Arige et al [1] investigated the functional importance of specific Ca2+ -coordinating residues, unambiguously confirming the activating Ca2+ binding site in the IP3R.

查看译文

关键词

Calcium release channels,Calcium signaling,Calcium binding site,Ryanodine receptor,Inositol 1,4,5-trisphosphate receptor

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要

Structural and functional conservation of the activating Ca2+ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors

Structural and functional conservation of the activating Ca²⁺ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors