An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research（2023）
摘要
We report on the discovery of a novel epigenetic phenotype associated with resistance to ICIs that may pave the way to better personalizing patients' treatments. See related commentary by Zhou and Kim, p. 1170.
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关键词
enhancer demethylator phenotype converged,immune checkpoint inhibitors,clear-cell
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