Corticotropin-releasing factor receptor agonists decrease interstitial cells of Cajal in murine colon.

Xu Huang,Jun-Ping Ao,Han-Yue Fu,Hong-Li Lu,Wen-Xie Xu

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society（2023）

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摘要

All these results suggest that CRF may be involved in the abnormality of colonic motility through peripheral CRF to decrease the number and function of ICC, which provides a potential target for treating stress-induced gastrointestinal motility disorder.

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关键词

CRF1,CRF2,ICC,murine colon,stress

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