Proximity-driven bioorthogonal reactions via DNA circuits enable the accurate aptasensing of non-nucleic acid targets.
Chemical communications (Cambridge, England)(2022)
摘要
Tetrazine-mediated bioorthogonal reactions were rationally coupled with DNA cascade circuits to enable proximal decaging, which allowed the construction of a fluorogenic aptasensor for the accurate and amplified sensing of non-nucleic acid targets in live cells.
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