Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection.
Cell reports. Medicine(2022)
摘要
Bharadwaj et al. demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies.
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关键词
fc glycosylation,antibody-mediated
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