Prognosis of Patients With Heart Failure Receiving Autologous Myoblast Patches - Comparison of Single-Arm Trial Data to Registry Data.
Circulation journal : official journal of the Japanese Circulation Society（2023）
摘要
This small single-arm trial using RMST analyses was able to detect the efficacy of AMP transplantation for advanced heart failure (compared with a registry-based control group), with better survival until 3.5 years. This approach may be useful for efficacy analyses in regenerative medicine, where traditional clinical trials are difficult.
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关键词
Autologous myoblast patch,Clinical trial,Regenerative medicine,Restricted mean survival time analysis,Single-arm trial
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