Angelica Yinzi alleviates 1-chloro-2,4-dinitrobenzene-induced atopic dermatitis by inhibiting activation of NLRP3 inflammasome and down-regulating the MAPKs/NF-kB signaling pathway

Wei Liu,Wanci Song,Yang Luo,Hanxiong Dan,Li Li, Zhouyang Zhang,Daonian Zhou,Pengtao You

Saudi Pharmaceutical Journal（2022）

引用 8|浏览4

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摘要

These findings revealed that AYZ effectively suppressed AD-induced skin inflammation by inhibiting the activation of the NLRP3 inflammasome and the MAPKs/NF-kB signaling. Therefore, AYZ is a potential therapeutic agent against AD in the clinical setting.

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关键词

Angelica Yinzi,Atopic dermatitis,MAPK,NLRP3,Inflammation

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