Early-onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late-onset.

Adrià Tort-Merino,Neus Falgàs,Isabel E Allen,Mircea Balasa,Jaume Olives,José Contador,Magdalena Castellví,Jordi Juncà-Parella,Núria Guillén,Sergi Borrego-Écija,Bea Bosch,Guadalupe Fernández-Villullas,Oscar Ramos-Campoy,Anna Antonell,Lorena Rami,Raquel Sánchez-Valle,Albert Lladó

Annals of clinical and translational neurology（2022）

引用 7|浏览5

暂无评分

摘要

Age of onset is a main factor shaping the cognitive trajectories in AD patients, with younger age driving to a steeper decline of the non-memory domains. Years of education are related to a transversal decline in all cognitive domains and APOE ε4 status to a specific decline in memory performance in EOAD.

查看译文

关键词

cognitive decline,alzheimer,distinct neuropsychological profile

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要