Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin.

Futoshi Furuya,Yoshihito Fujita,Naomi Matsuo,Hiroto Minamino,Yasuo Oguri,Nozomi Isomura,Kaori Ikeda, Kohei Takesue,Ying Li,Aki Kondo,Fumika Mano,Nobuya Inagaki

EBioMedicine（2022）

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摘要

AstraZeneca K.K., Ono Pharmaceutical Co., Ltd., Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan Society for the Promotion of Science (JSPS), Japan Agency for Medical Research and Development (AMED), Novo Nordisk Pharma Ltd., and Japan Foundation for Applied Enzymology, and MSD Life Science Foundation International.

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关键词

Autophagy,Biomarker,Branched chain amino acids (BCAAs),Diabetes,Liver,Sodium glucose co-transporter 2 (SGLT2) inhibitor

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