Impact of Elexacaftor–tezacaftor–ivacaftor on Bacterial Colonization and Inflammatory Responses in Cystic Fibrosis
Pediatric Pulmonology(2022)
摘要
Cystic fibrosis (CF) is a multisystem disease with progressive deterioration. Recently, CF transmembrane conductance regulator (CFTR) modulator therapies were introduced that repair underlying protein defects. Objective of this study was to determine the impact of elexacaftor–tezacaftor–ivacaftor (ETI) on clinical parameters and inflammatory responses in people with CF (pwCF).
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关键词
CFTR,cystic fibrosis,infection,inflammation
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