Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer.

Matthew R Trendowski,Christopher Sample,Tara Baird,Azita Sadeghpour,David Moon,Julie J Ruterbusch,Jennifer L Beebe-Dimmer,Kathleen A Cooney

JCO precision oncology（2022）

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摘要

Variants in DDR genes and may be important cancer risk factors for Black men diagnosed with early-onset prostate cancer, and are more frequently observed in men with a family history of cancer.

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关键词

prostate cancer,germline variants,dna damage repair genes,dna damage repair,early-onset

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