A Novel Index, Chinese Visceral Adiposity Index is Closely Associated with Urinary Albumin-Creatinine Ratio in Chinese Community Adults, Especially in Hypertensive or Hyperglycemic Population: Results from the REACTION Study.
Journal of diabetes(2022)
摘要
BackgroundThe association between the Chinese Visceral Adiposity Index (CVAI) and urinary albumin to creatinine ratio (UACR) has not been illustrated. The current study aimed to investigate the association between CVAI and UACR and to compare the discriminative power of CVAI, triglyceride, body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with UACR in the Chinese community population. MethodsThis study included 34 732 participants from the REACTION (Risk Evaluation of cAncers in Chinese diabeTic Individuals) study. Binary logistic regression analyses were performed to detect the association between CVAI, triglyceride, BMI, WC, WHR and UACR. ResultsBinary logistic regression analysis showed that, after adjusting for potential confounders, in women, CVAI (odds ratio [OR]:1.16, 95% confidence interval [CI]: 1.01-1.34) and triglyceride (OR: 1.18, 95% CI: 1.04-1.33) were associated with UACR, whereas BMI, WC, and WHR were not associated with UACR; in men, CVAI (OR: 1.24, 95% CI: 1.02-1.50), WC (OR: 1.21, 95% CI 1.00-1.48), and triglycerides (OR: 1.18, 95% CI 0.97-1.44) were associated with UACR, whereas BMI and WHR were not associated with UACR. Stratified analysis showed that the correlation between CVAI and UACR was stronger in the population with 5.6 <= fasting blood glucose (FBG) <7.0 or 7.8 <= post-load blood glucose (PBG) <11.1 mmol/L, FBG >= 7.0 or PBG >= 11.1, systolic blood pressure >= 140 mmHg or diastolic blood pressure >= 90 mmHg. ConclusionsIn the Chinese general population, CVAI and UACR were significantly associated in both genders. At higher CVAI levels, the population with prediabetes, diabetes, and hypertension has a more significant association between CVAI and UACR.
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关键词
Chinese Visceral Adiposity Index,diabetic complications,diabetic nephropathy,obesity,urinary albumin to creatinine ratio
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