Age differences in the association between sleep and Alzheimer's disease biomarkers in the EPAD cohort.

Sharon L Naismith,Yue Leng,Jake R Palmer,Brendan P Lucey

Alzheimer's & dementia (Amsterdam, Netherlands)（2022）

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摘要

This study shows age differences in the link between sleep and AD biomarkers.Shorter sleep was associated with greater p-tau/Aβ42 ratio in middle age.The association was independent of genetic, vascular, and neuroimaging markers of AD.

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Alzheimer's,Aβ42,EPAD,PSQI,biomarkers,p‐tau,sleep,sleep duration,sleep efficiency,sleep latency

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