Conversion of osteoporotic vertebral fracture severity score to osteoporosis T-score equivalent status: a framework and a comparative study of Hong Kong Chinese and Rome Caucasian older women
ARCHIVES OF OSTEOPOROSIS(2022)
摘要
Summary We explored how the severity of radiological osteoporotic vertebral fracture (OVF) can be converted to the equivalent T-score values. Introduction To perform a study to define what portion of older community women with what severity of radiographic OVF correspond to what low T-score status. Methods There were age-matched 301 Italian community women and 301 Chinese community women (sub-group A, age, 73.6 ± 6.1 years). In addition, Chinese sub-groups B and C included 110 community women (age, 68.9 ± 5.5 years) and 101 community women (age: 82.2 ± 4.3 years), respectively. For each vertebra in women, a score of 0, − 0.5, − 1, − 1.5, − 2, − 2.5, and − 3 was assigned for no OVF or OVF of < 20%, ≥ 20 ~ 25%, ≥ 25% ~ 1/3, ≥ 1/3 ~ 40%, ≥ 40%–2/3, and ≥ 2/3 vertebral height loss, respectively, OVFss was defined as the summed score of vertebrae T4 to L5. OVFss and T-scores were ranked from the smallest to the largest values. Results For the Chinese total group (sub-groups A, B, and C together), OVFss = − 1 corresponded to lowest T-score (lowest T-score of lumbar spine, femoral neck, and total hip) of − 3.4 ~ − 3.2. OVFss ≤ − 1.5 corresponded to femoral neck T-score ≤ − 2.5. OVFss = −1.5 corresponded to a mean femoral neck T-score of − 3.0, − 2.6, and − 2.4, among Chinese sub-groups B, A, and C subjects, respectively. For Italians, all cases with OVFss ≤ − 1 had lowest T-score ≤ − 2.5. For cases with femoral neck T-score = − 2.5, 41.7% had OVFss = − 1.5, and 58.3% had OVFss = − 1. Conclusion For older women, statistically OVFss ≤ − 1 suggests this subject is osteoporotic according to lowest T-score. If using femoral neck T-score, OVFss ≤ − 1.5 qualifies osteoporosis diagnosis.
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关键词
Osteoporosis,Osteoporotic vertebral fracture,Bone mineral density,T-score,Spine
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