Antibodies Produced in Response to a Live-Attenuated Dengue Vaccine are Functional in Activating the Complement System.

The Journal of infectious diseases(2022)

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摘要
These results indicate that antibodies produced after TAK-003 vaccination are functional in both activating CS and neutralizing virus infection by all DENV serotypes, which may contribute to efficacy of TAK-003.
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关键词
C1q,DENV,IgA,IgG1,IgM,TAK-003,avidity index,complement-fixing antibodies
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