Real World Performance of The Afirma Genomic Sequencing Classifier (GSC) - A Meta-analysis.

Christian E Nasr,Massimiliano Andrioli,Mayumi Endo,R Mack Harrell,Masha J Livhits,Ibitoro Osakwe,Preethi Polavarapu,Allan Siperstein,Shuanzeng Wei,Xingyu Zheng,Ruochen Jiang,Yangyang Hao,JIng Huang,Joshua P Klopper,Richard T Kloos,Giulia Kennedy,Trevor E Angell

The Journal of clinical endocrinology and metabolism（2022）

引用 11|浏览14

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摘要

RW data for the Afirma GSC demonstrates significantly better oSP and oPPV performance compared to the VS, indicating an increased yield of cancers for resected GSC suspicious nodules. The higher BCR likely increases the overall rate of clinical observation in lieu of surgery.

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关键词

genomic sequencing classifier,real world,indeterminate thyroid nodule,benign call rate,risk of malignancy

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