Decreased Serum Osteocalcin is an Independent Risk Factor for Metabolic Dysfunction-Associated Fatty Liver Disease in Type 2 Diabetes.

Yu-Jie Wang,Chun-Hua Jin,Jiang-Feng Ke,Jun-Wei Wang,Yi-Lin Ma,Jun-Xi Lu,Mei-Fang Li,Lian-Xi Li

Diabetes, metabolic syndrome and obesity : targets and therapy（2022）

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摘要

Serum OCN levels were independently and negatively associated with the presence of MAFLD in Chinese T2DM patients, partially due to the improvement of insulin resistance and inflammation mediated by OCN. Serum OCN may be used as a biomarker to assess the risk of MAFLD in T2DM patients.

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关键词

diabetes mellitus,inflammation,insulin resistance,metabolic dysfunction-associated fatty liver disease,osteocalcin,type 2

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