Chapter 9. Advanced Scaffold Fabrication using Additive Manufacturing

Scaffolds are an essential component of tissue engineering and modeling that must meet tissue- and/or pathophysiological-specific design criteria. Recent advances in additive manufacturing have enabled the production of scaffolds with complex architectures that are able to mimic the rich chemical, physical, and mechanical characteristics of the tumor niche. In this chapter, additive manufacturing techniques to fabricate scaffolds, including key design considerations, materials used, advantages and disadvantages, and applications in tumor and tumor microenvironment modeling will be reviewed.