Cutaneous Leukocytoclastic Vasculitis as the Presenting Sign of Systemic Lupus Erythematosus

Cutaneous involvement occurs in 72-85% of cases of systemic lupus erythematosus and may be the first clinical sign in up to 25% of cases. 1. Chottawornsak N Rodsaward P Suwannachote S et al. Skin signs in juvenile- and adult-onset systemic lupus erythematosus: clues to different systemic involvement. Lupus. 2018; 27: 2069-2075https://doi.org/10.1177/0961203318805851 Crossref Scopus (8) Google Scholar Recognizing these cutaneous manifestations is essential to early diagnosis and management. 1. Chottawornsak N Rodsaward P Suwannachote S et al. Skin signs in juvenile- and adult-onset systemic lupus erythematosus: clues to different systemic involvement. Lupus. 2018; 27: 2069-2075https://doi.org/10.1177/0961203318805851 Crossref Scopus (8) Google Scholar Here, we present a case of systemic lupus erythematosus with cutaneous leukocytoclastic vasculitis—rare presenting sign of systemic lupus erythematosus 2 Kallas R Goldman D Petri MA. Cutaneous vasculitis in SLE. Lupus Sci Med. 2020; 7e000411https://doi.org/10.1136/lupus-2020-000411 Crossref Google Scholar —as the initial manifestation to highlight the opportunity for prompt diagnosis and management of systemic lupus erythematosus. 3 Barile-Fabris L Hernández-Cabrera MF Barragan-Garfias JA. Vasculitis in systemic lupus erythematosus. Curr Rheumatol Rep. 2014; 16: 440https://doi.org/10.1007/s11926-014-0440-9 Crossref PubMed Scopus (99) Google Scholar