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Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation

Journal of Cardiovascular Translational Research(2022)SCI 3区

Örebro University

Cited 0|Views11
Abstract
Intra-aortic balloon pump (IABP) use during CPR has been scarcely studied. Intra-caval balloon pump (ICBP) may decrease backward venous flow during CPR. Mechanical chest compressions (MCC) were initiated after 10 min of cardiac arrest in anesthetized pigs. After 5 min of MCC, IABP (n = 6) or ICBP (n = 6) was initiated. The MCC device and the IABP/ICBP had slightly different frequencies, inducing a progressive peak pressure phase shift. IABP inflation 0.15 s before MCC significantly increased mean arterial pressure (MAP) and carotid blood flow (CBF) compared to inflation 0.10 s after MCC and to MCC only. Coronary perfusion pressure significantly increased with IABP inflation 0.25 s before MCC compared to inflation at MCC. ICBP inflation before MCC significantly increased MAP and CBF compared to inflation after MCC but not compared to MCC only. This shows the potential of IABP in CPR when optimally synchronized with MCC. The effect of timing of intra-aortic balloon pump (IABP) inflation during mechanical chest compressions (MCC) on hemodynamics. Data from12 anesthetized pigs.
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Heart arrest,Cardiopulmonary resuscitation,Counterpulsation,Hemodynamics
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要点】:本研究探讨了在实验性非创伤性心脏骤停和心肺复苏中,主动脉内和腔静脉内气囊泵的同步使用对血流动力学的影响,发现优化同步的主动脉内气囊泵(IABP)可显著提高平均动脉压和颈动脉血流量。

方法】:使用机械胸外按压(MCC)对麻醉猪进行心肺复苏,并在MCC后分别引入IABP和腔静脉内气囊泵(ICBP),观察不同同步时间下IABP和ICBP对血流动力学的影响。

实验】:在12只麻醉猪上进行了实验,通过在不同时间点(相对于MCC)充气IABP和ICBP,测量平均动脉压(MAP)、颈动脉血流量(CBF)和冠状动脉灌注压的变化。结果显示,IABP在MCC前0.15秒充气能显著提高MAP和CBF,而ICBP在MCC前充气也能提高MAP和CBF,但与仅进行MCC相比无显著差异。数据集名称未在摘要中提及。