Structural Correlates of Overt Sentence Reading in Mild Cognitive Impairment and Mild-to-Moderate Alzheimer's Disease.

Céline De Looze,Amir Dehsarvi, Narin Suleyman,Lisa Crosby,Belinda Hernández,Robert F Coen,Brian A Lawlor,Richard B Reilly

Current Alzheimer research（2022）

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摘要

The temporal organization of speech in overt sentence reading reflects underlying volume reductions. It may represent a sensitive marker for early assessment of structural changes and cognitive- linguistic deficits associated with healthy aging, MCI, and AD.

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关键词

Alzheimer disease,cognitive aging,functional neuroimaging,genetic programming,machine learning,mild cognitive impairment,sentence reading,temporal speech features

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