Cancer immunotherapy with CAR T cells: well-trodden paths and journey along lesser-known routes.

Radiology and oncology(2022)

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摘要
Cancer immunotherapy with CAR T cells represents a paradigm shift in the treatment of certain blood cancers that do not respond to other available treatment options. Well-trodden paths taken by pioneers led to the first clinical approval, and now the journey continues down lesser-known paths to treat a variety of cancers and other serious diseases with CAR T cells.
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关键词
adoptive cell therapy,cancer,cellular immunotherapy,chimeric antigen receptor,gene-engineered immune cells
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