The PRSS3P2 and TRY7 deletion copy number variant modifies risk for chronic pancreatitis Emmanuelle Masson , Maren Ewers , Sumit Paliwal , Kiyoshi Kume , Virginie Scotet , David N Cooper , Vinciane Rebours , Louis Buscail , Karen Rouault , Amandine Abrantes , Lina Aguilera Munoz , Jérémie Albouys , Laurent Alric , Xavier Amiot , Isabelle Archambeaud , Solène Audiau , Laetitia Bastide , Julien Baudon , Guy Bellaiche , Serge Bellon , Valérie Bertrand , Karine Bideau , Kareen Billiemaz , Claire Billioud , Sabine Bonnefoy , Corinne Borderon , Barbara Bournet , Estelle Breton , Mathias Brugel , Louis Buscail , Guillaume Cadiot , Marine Camus , Marine Carpentier-Pourquier , Patrick Chamouard , Ulriikka Chaput , Jian-Min Chen , Franck Cholet , Dragos Marius Ciocan , Christine Clavel , Benoit Coffin , Laura Coimet-Berger , Simona Cosconea , Isabelle Creveaux , Adrian Culetto , Oussama Daboussi , Louis De Mestier , Thibault Degand , Christelle D'engremont , Bernard Denis , Solène Dermine , Desgrippes , Augustin Drouet D'Aubigny , Raphaël Enaud , Alexandre Fabre , Claude Férec , Dany Gargot , Eve Gelsi , Elena Gentilcore , Rodica Gincul , Emmanuelle Ginglinger-Favre , Marc Giovannini , Cécile Gomercic , Hannah Gondran , Thomas Grainville , Philippe Grandval , Denis Grasset , Stéphane Grimaldi , Sylvie Grimbert , Hervé Hagege , Sophie Heissat , Olivia Hentic , Anne Herber-Mayne , Marc Hervouet , Solene Hoibian , Jérémie Jacques , Bénédicte Jais , Mehdi Kaassis , Stéphane Koch , Elodie Lacaze , Joël Lacroute , Thierry Lamireau , Lucie Laurent , Xavier Le Guillou , Marc Le Rhun , Sarah Leblanc , Philippe Levy , Astrid Lievre , Diane Lorenzo , Frédérique Maire , Kévin Marcel , Emmanuelle Masson , Jacques Mauillon , Stéphanie Morgant , Driffa Moussata , Nelly Muller , Sophie Nambot , Bertrand Napoleon , Anne Olivier , Maël Pagenault , Anne-Laure Pelletier , Olivier Pennec , Fabien Pinard , Mathieu Pioche , Bénédicte Prost , Lucille Queneherve , Vinciane Rebours , Noemi Reboux , Samia Rekik , Ghassan Riachi , Barbara Rohmer , Bertrand Roquelaure , Isabelle Rosa Hezode , Florian Rostain , Jean-Christophe Saurin , Laure Servais , Roxana Stan-Iuga , Clément Subtil , Jérémy Tanneche , Charles Texier , Lucie Thomassin , David Tougeron , Lucine Vuitton , Timothée Wallenhorst , Marc Wangerme , Hélène Zanaldi , Frank Zerbib , Seema Bhaskar , Kazuhiro Kikuta , G Venkat Rao , Shin Hamada , D Nageshwar Reddy , Atsushi Masamune , Giriraj Ratan Chandak , Heiko Witt , Claude Férec , Jian-Min Chen Pancreatology（2023）
摘要
The common PRSS3P2 and TRY7 deletion CNV was associated with a reduced risk for CP. This finding provides additional support for the emerging view that dysregulated PRSS2 expression represents a discrete mechanism underlying CP predisposition or protection.
更多 查看译文
关键词
Causal variant, Case-control study, Genetic predisposition to disease, Pancreatic tissue, rs10273639
AI 理解论文
溯源树
样例
