The Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) as a Novel Therapeutic Target in Mantle Cell Lymphoma.

Jiao Li,Hui Yu,Xing Wang,Yingying Ye,Wei Fang,Ning Ding,Lan Mi,Lingyan Ping,Xiaogan Wang,Yuqin Song,Jun Zhu

Cancer control : journal of the Moffitt Cancer Center（2022）

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摘要

SGK1 may be a novel candidate therapeutic target and simultaneous inhibition of SGK1 and BTK may be a promising therapeutic strategy for MCL patients. Further pre-clinical and even clinical studies of SGK1 inhibitor or combination with BTK inhibitor are essential.

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关键词

bruton tyrosine kinase,drug combination,mantle cell lymphoma,serum- and glucocorticoid-inducible kinase 1,targeted therapy

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