Intercommunication between metal ions and amyloidogenic peptides or proteins in protein misfolding disorders

•Comprehensive coordination modes of biologically relevant Cu(I/II) and Zn(II) to amyloidogenic peptides or proteins are summarized.•Distinct impact of transition metal ions on the aggregation of amyloidogenic peptides or proteins are described.•Oxidative modifications of amyloidogenic peptides or proteins mediated by metal-catalyzed reactions are outlined.