Circadian rest-activity rhythm and longitudinal brain changes underlying late-life cognitive decline.

Psychiatry and clinical neurosciences(2023)

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摘要
The findings indicate that delayed acrophase in late life may cause or predict hypometabolism at AD-signature brain regions, which underlies cognitive decline in the near future.
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关键词
Alzheimer disease,cognitive decline,neurodegeneration,older adults,rest-activity rhythm
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