om92 , a glp-1 enhancer mutation, is an allele of ekl-1 .

Germline stem cell proliferation in requires activation of the GLP-1/Notch receptor, which is located on the germline plasma membrane and encoded by the gene. We previously identified several genes whose products directly or indirectly promote activity of the GLP-1 signaling pathway by finding mutations that enhance the germline phenotype of a allele, . Here, we report phenotypic and molecular analysis of a new allele, , that enhances the phenotype. is a 244 bp deletion predicted to generate a frameshift and premature termination codon, yielding a severely truncated protein, suggesting it is a null allele.