Mouse Adapted SARS‐CoV‐2 Induces ‘long‐covid’ Neuropathology in BALB/c Mice
Alzheimer's & Dementia(2022)
摘要
COVID‐19 survivors develop neuro‐psychological symptoms as post‐COVID 19 syndromes, although the pathophysiology remains elusive. SARS‐CoV‐2 MA10 (MA10) is a model of mouse‐adapted SARS‐CoV‐2 that recapitulates acute respiratory distress syndrome observed in humans. However, the consequence of MA10 infection on brain pathology is not yet evaluated. The study aimed to evaluate the long‐term consequence of MA10 infection on blood‐brain barrier (BBB) integrity and neuroinflammation
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关键词
Neuroinflammation
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