Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan.

Maria Valkovskaya,Arsalan Hassan,Eirini Zartaloudi,Fahad Hussain,Muhammad Umar,Bakht Khizar, Inzemam Khattak, Shamshad Ahmed Gill,Shams-Ud-Din Ahmad Khan,Imtiaz Ahmad Dogar,Ali Burhan Mustafa,Moin Ahmed Ansari, Syed Qalb I Hyder,Muhammad Ali, Nilofar Ilyas, Parveen Channar,Nazish Mughal, Sumera Channa,Khalid Mufti, Ali Ahsan Mufti,Mian Iftikhar Hussain,Sadia Shafiq,Muhammad Tariq,Muhammad Kamran Khan, Shahzad Tahir Chaudhry, Abdul Rashid Choudhary, Mian Nizam Ali,Gohar Ali,Ashfaq Hussain, Muhammad Rehman, Noman Ahmad,Saeed Farooq,Farooq Naeem,Tanveer Nasr,Glyn Lewis,James A. Knowles,Muhammad Ayub,Karoline Kuchenbaecker

Psychiatric genetics（2022）

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摘要

DIVERGE is a carefully designed case-control study of MDD in Pakistan that captures diverse risk factors. As the largest genetic study in Pakistan, DIVERGE helps address the severe underrepresentation of people from South Asian countries in genetic as well as psychiatric research.

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关键词

depression,genome-wide association study,major depressive disorder,Pakistan,protocol,risk factor

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