Outcomes of Older Adults with Non-Hodgkin Lymphoma Undergoing Autologous Stem Cell Transplantation: A Mayo Clinic Cohort Analysis

Transplantation and Cellular Therapy(2023)

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摘要
•Nonrelapse mortality after autologous stem cell transplantation (ASCT) in older patients with lymphoma was low and has improved over time.•Older patients with a high Hematopoietic Cell Transplantation Comorbidity Index had inferior outcomes after ASCT. Age should not be the sole factor in determining for eligibility for ASCT.•Patients who were progression-free at 2 years (achieving PFS24) had excellent survival and low relapse, suggesting that ASCT may cure a subset of older patients with lymphoma.
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关键词
Elderly,Autologous stem cell transplantation,Lymphoma,Geriatric,Mortality
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