Unimodal vs. Multimodal Prediction of Antenatal Depression from Smartphone-based Survey Data in a Longitudinal Study

ABSTRACTAntenatal depression impacts 7-20% of women globally, and can have serious consequences for both the mother and the infant. Preventative interventions are effective, but are cost-efficient only among those at high risk. As such, being able to predict and identify those at risk is invaluable for reducing the burden of care and adverse consequences, as well as improving treatment outcomes. While several approaches have been proposed in the literature for the automatic prediction of depressive states, there is a scarcity of research on automatic prediction of perinatal depression. Moreover, while there exist some works on the automatic prediction of postpartum depression using data collected in clinical settings and applied the model to a smartphone application, to the best of our knowledge, no previous work has investigated the automatic prediction of late antenatal depression using data collected via a smartphone app in the first and second trimesters of pregnancy. This study utilizes data measuring various aspects of self-reported psychological, physiological and behavioral information, collected from 915 women in the first and second trimester of pregnancy using a smartphone app designed for perinatal depression. By applying machine learning algorithms on these data, this paper explores the possibility of automatic early detection of antenatal depression (i.e., during week 36 to week 42 of pregnancy) in everyday life without the administration of healthcare professionals. We compare uni-modal and multi-modal models and identify predictive markers related to antenatal depression. With multi-modal approach the model reaches a BAC of 0.75, and an AUC of 0.82.