Structural Cerebral Network Differences in Prodromal Alzheimer's Disease and Prodromal Dementia with Lewy Bodies.

Miho Ota,Kiyotaka Nemoto,Miyuki Nemoto,Yuriko Numata,Ayako Kitabatake,Yasunori Yamada,Kaoru Shinkawa,Masatomo Kobayashi,Tetsuaki Arai

Dementia and Geriatric Cognitive Disorders（2022）

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摘要

We found the change of degree in the patients with MCI-AD and with MCI-LB, compared with healthy controls. These findings were consistent with the past single-photon emission computed tomography studies focusing on AD and DLB. The disease-related difference in the cerebral neural network might provide an adjunct biomarker for the early detection of AD and DLB.

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关键词

Magnetic resonance imaging,Mild cognitive impairment due to Alzheimer’s disease,Mild cognitive impairment with Lewy bodies,Neural network,Small-world property

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