4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: Synthesis, Antiviral Activity, and Electrochemical Characteristics

R. A. Drokin, E. A. Fesenko,P. N. Mozharovskaia,M. V. Medvedeva,T. S. Svalova,A. N. Kozitsina,Ya. L. Esaulkova,A. S. Volobueva,V. V. Zarubaev,V. L. Rusinov

Russian chemical bulletin（2022）

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摘要

A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1- c ][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.

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关键词

3-nitroazolo[5,1-c][1,4]triazines,azolotriazines,triazines,antiviral activity,Coxsackie B3 virus,voltammetry,electrochemical properties

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