Epicardial Fat Volume Evaluated with Multidetector Computed Tomography and Other Risk Factors for Prevalence of Three-Vessel Coronary Lesions
European journal of medical research(2022)
摘要
Purpose To retrospectively investigate the epicardial fat volume with multidetector computed tomography (MDCT) and other risk factors for the prevalence of three-vessel coronary lesion. Materials and methods MDCT was performed on 424 subjects with or without three-vessel coronary lesion. Blood was tested for triglyceride, high-density lipoprotein (HDL), low-density lipoprotein (LDL), apolipoprotein A (ApoA), apolipoprotein B (ApoB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lipoprotein a, and fasting blood glucose. Results Among all the subjects, a significant ( P < 0.05) negative linear correlation existed between age and ALT or ALT/AST. The epicardial fat had a significant ( P < 0.05) negative linear correlation with HDL and Apo A but a positive correlation with age and ApoB/ApoA. The epicardial fat volume and the fasting blood glucose were significantly ( P = 0.001) greater in the patients than in the control group, whereas HDL and Apo A were both significantly ( P < 0.0001) smaller in the patients than in the control groups. A significant prediction value ( P < 0.05) existed in age increase, male gender, epicardial fat increase, low HDL, high LDL, and elevated fasting blood glucose. Conclusion Three-vessel coronary lesions are more prevalent in subjects with greater volume of epicardial fat and in male gender.
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关键词
Three-vessel coronary lesion,Computed tomography,Epicardial fat,Risk factor,Biochemical marker
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