Representing Steerable Bases for cryo-EM in ASPIRE
2022 IEEE 18th International Conference on e-Science (e-Science)(2022)
摘要
An introduction to the mathematical problem of cryo-electron microscopy (cryo-EM) is given, along with an overview of ASPIRE, an open-source Python package for processing cryo-EM image data. ASPIRE uses unique Fourier basis representations for images of cryo-EM particles. The challenge of representing these mathematical structures within the ASPIRE codebase was addressed by building an extensible class hierarchy using mixins.
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关键词
cryo EM,fourier bessel,steerable basis,mixins,scientific software,cryo electron microscopy,aspire,python,open source
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