Risk of urinary stone formation associated to proton pump inhibitors: A systematic review and metanalysis.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica(2022)

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摘要
PPIs showed an association with urinary calculi in patients included in the studies included in this review. If these data will be confirmed in adequately powered randomized trials, clinicians may consider limiting the long-term use of PPIs, to avoid unnecessary prolongation of treatment. Urinary magnesium and citrate should be evaluated in renal stone forming patients taking PPIs to supplement their intake when requested.
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关键词
Proton pump inhibitors, Urinary calculi, H2-receptor blockers, Magnesium, Citrate
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