Dual orexin receptor antagonists for treatment of insomnia: A systematic review and meta-analysis on randomized, double-blind, placebo-controlled trials of suvorexant and lemborexant.

Habibolah Khazaie,Masoud Sadeghi,Sepideh Khazaie,Max Hirshkowitz,Amir Sharafkhaneh

Frontiers in psychiatry（2022）

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摘要

The present meta-analysis reported that suvorexant and lemborexant are efficacious and safe agents for the patients with insomnia. Further data in patients with insomnia and various comorbid conditions are needed.

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关键词

insomnia,lemborexant,meta-analysis,orexin receptor antagonist,randomized trial,suvorexant

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