Primary Radiation as an Alternative Option for Early-Stage Cervical Cancer.

The standard of care for locally advanced cervical cancer is concurrent chemoradiotherapy (CRT) followed by image guided brachytherapy. Surgery is not indicated for initial debulking before initiation of CRT or as adjuvant treatment after completion of CRT. 1 Keys HM Bundy BN Stehman FB et al. Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med. 1999; 340: 1154-1161 Crossref PubMed Scopus (1703) Google Scholar However, the question remains: what is the best strategy for the management of early-stage, operable disease?